Metabolosomes: Difference between revisions
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{{OrganelleInfoBox | {{OrganelleInfoBox | ||
| organelle = Metabolosomes | | organelle = Metabolosomes | ||
| icon = | | icon = MetabolosomeIcon.png | ||
| image = | | image = MetabolosomeOrganelle.png | ||
| cost = 45 | | cost = 45 | ||
| requiresNucleus = No | | requiresNucleus = No | ||
| Line 17: | Line 17: | ||
}} | }} | ||
'''Metabolosomes''' perform '''Protein Respiration''', a form of '''Aerobic Respiration''' inferior to that of '''[[Mitochondrion|Mitochondria]]'''. It is the conversion of '''Glucose''' {{CompoundIcon|image=GlucoseIcon.png|internalName=glucose}} into '''ATP''' {{CompoundIcon|image=ATPIcon.png|internalName=atp}} with the use of '''Oxygen''' {{CompoundIcon|image=OxygenIcon.png|internalName=oxygen}}. | |||
== Requirements == | == Requirements == | ||
| Line 25: | Line 25: | ||
== Processes == | == Processes == | ||
'''Protein Respiration''': '''Glucose''' | '''Protein Respiration''': '''Glucose''' {{CompoundIcon|image=GlucoseIcon.png|internalName=glucose}} + '''Oxygen''' {{CompoundIcon|image=OxygenIcon.png|internalName=oxygen}} → '''ATP''' {{CompoundIcon|image=ATPIcon.png|internalName=atp}} | ||
A method of energy production, superior to that in '''[[Cytoplasm]]''' but inferior to '''[[Mitochondrion|Mitochondria]]'''. Requires a steady influx of '''Glucose''' {{CompoundIcon|image=GlucoseIcon.png|internalName=glucose}}. Rate scales with the concentration of environmental '''Oxygen''' {{CompoundIcon|image=OxygenIcon.png|internalName=oxygen}}. | |||
== Modifications == | == Modifications == | ||
| Line 43: | Line 43: | ||
== Strategy == | == Strategy == | ||
In many ways, '''Metabolosomes''' are an extension of '''[[Cytoplasm]]'''. A playstyle that works for the starting cell (LUCA) is likely to work for a cell built from '''Metabolosomes''' – simply gather '''Glucose''' {{CompoundIcon|image=GlucoseIcon.png|internalName=glucose}} from the environment. The difference is increased efficiency that can support more organelles with wider functions, such as '''[[Perforator Pilus|Perforator Pili]]''' or '''[[Flagellum|Flagella]]'''. | |||
== | However, natural '''Glucose''' {{CompoundIcon|image=GlucoseIcon.png|internalName=glucose}} concentrations in the environment decrease over the course of the game, so it may be advisable to switch to new food sources later on. | ||
Once a cell evolves a '''[[Nucleus]]''', it's advisable to replace '''Metabolosomes''' with their eukaryotic equivalent, '''[[Mitochondrion|Mitochondria]]''', since these are much more efficient. | |||
== Scientific Background == | |||
== | |||
Unlike eukaryotes, prokaryote organelles do not have membranes. Instead, prokaryotes like bacteria construct compartments out of proteins. A '''Metabolosome''' is an example of such a compartment, officially referred to as a Bacterial MicroCompartment (BMC). BMCs consist of a polyhedral protein shell around 100-200 nm in size that looks similar to a virus capsid. The proteins that make up the shell typically have (semi-permeable) pores that allow different compounds (substrates and products) in and out of the organelle. They concentrate enzymes and proteins involved in specific metabolic processes in one spot, ensuring their success. The protein shell also acts as a physical barrier, allowing BMCs to conduct metabolic reactions that create toxic or unstable intermediate compounds. | |||
'''Metabolosomes''' are a catabolic type of BMC, and are involved in the degradation of different carbon sources such as glycerol and amino acids. There is no clear evidence that the process of breaking down '''Glucose''' {{CompoundIcon|image=GlucoseIcon.png|internalName=glucose}} takes place in metabolosomes, however it is not unreasonable to assume that it could do so. | |||
The actual process of breaking down glucose for energy takes place in several steps in both prokaryotes and eukaryotes. The only difference is where some of the enzymes are located and organized. | |||
Read more on this organelle's [https://en.wikipedia.org/wiki/Bacterial_microcompartment#Metabolosomes%3A_aldehyde_oxidation Wikipedia page]. | |||
Latest revision as of 23:22, 23 February 2024
| Organelle Details | |
|---|---|
| Metabolosomes |  |
| |
| Base Cost (MP) | 45 |
| Requires Nucleus | No |
| Processes | Protein Respiration |
| Enzymes | None |
| Size (Hexes) | 1 |
| Osmoregulation Cost | 1 |
| Storage | 0.5 |
| Unique | No |
| Upgrades | None |
| Internal Name | metabolosome |
Metabolosomes perform Protein Respiration, a form of Aerobic Respiration inferior to that of Mitochondria. It is the conversion of Glucose 
into ATP 
with the use of Oxygen 
.
Requirements
No requirements
Processes
Protein Respiration: Glucose + Oxygen → ATP
A method of energy production, superior to that in Cytoplasm but inferior to Mitochondria. Requires a steady influx of Glucose . Rate scales with the concentration of environmental Oxygen .
Modifications
No modifications.
Effects
No effects.
Upgrades
No upgrades.
Strategy
In many ways, Metabolosomes are an extension of Cytoplasm. A playstyle that works for the starting cell (LUCA) is likely to work for a cell built from Metabolosomes – simply gather Glucose from the environment. The difference is increased efficiency that can support more organelles with wider functions, such as Perforator Pili or Flagella.
However, natural Glucose concentrations in the environment decrease over the course of the game, so it may be advisable to switch to new food sources later on.
Once a cell evolves a Nucleus, it's advisable to replace Metabolosomes with their eukaryotic equivalent, Mitochondria, since these are much more efficient.
Scientific Background
Unlike eukaryotes, prokaryote organelles do not have membranes. Instead, prokaryotes like bacteria construct compartments out of proteins. A Metabolosome is an example of such a compartment, officially referred to as a Bacterial MicroCompartment (BMC). BMCs consist of a polyhedral protein shell around 100-200 nm in size that looks similar to a virus capsid. The proteins that make up the shell typically have (semi-permeable) pores that allow different compounds (substrates and products) in and out of the organelle. They concentrate enzymes and proteins involved in specific metabolic processes in one spot, ensuring their success. The protein shell also acts as a physical barrier, allowing BMCs to conduct metabolic reactions that create toxic or unstable intermediate compounds.
Metabolosomes are a catabolic type of BMC, and are involved in the degradation of different carbon sources such as glycerol and amino acids. There is no clear evidence that the process of breaking down Glucose takes place in metabolosomes, however it is not unreasonable to assume that it could do so.
The actual process of breaking down glucose for energy takes place in several steps in both prokaryotes and eukaryotes. The only difference is where some of the enzymes are located and organized.
Read more on this organelle's Wikipedia page.